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CD3 epsilon 抗体

This anti-CD3 epsilon antibody is a 仓鼠 单克隆 antibody detecting CD3 epsilon in FACS, WB, IHC, IP, IF 和 IHC (fro). Suitable for 小鼠.
产品编号 ABIN7470758
发货至: 中国

Quick Overview for CD3 epsilon 抗体 (ABIN7470758)

抗原

See all CD3 epsilon (CD3E) 抗体
CD3 epsilon (CD3E)

适用

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小鼠

宿主

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仓鼠

克隆类型

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单克隆

标记

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This CD3 epsilon antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 特异性

    Detects CD3 epsilon (CD3e), a 20kD transmembrane protein also known as CD3 or T3. CD3e is a member of the CD3 complex which consists of four subunits, gamma, delta, epsilon and zeta, and these are associated to the T cell receptor (TCR). TCR plays a critical role in T cell development and function, and is responsible for ligand recognition. It interacts non-covalently with the CD3 dimers delta/epsilon, gamma/epsilon and zeta/zeta which transduce signals from the TCR into the cell. CD3e is primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. The 145-2C11 antibody is useful for in vitro blocking and activation assays, as well as apoptosis induction and in vitro T cell depletions.

    纯化方法

    Protein G purified

    免疫原

    H-2K b - specific mouse cytotoxic T lymphocyte clone BM10-37.

    亚型

    IgG
  • 应用备注

    Approved: Flo, IF, IHC, IHC-Fr, IP, WB

    Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 1x10^6 cells in 100 μL. The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity Fc receptors.

    说明

    Target Species of Antibody: Mouse

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    PBS,  pH 7.2, 0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • 抗原

    CD3 epsilon (CD3E)

    别名

    CD3E

    背景

    Name/Gene ID: CD3E

    Synonyms: CD3E, CD3e antigen, CD3-epsilon, T-cell receptor epsilon chain, TCRE, T-cell receptors epsilon chain, T3E, CD3 Epsilon

    基因ID

    916

    途径

    TCR Signaling, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway
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